In anatomic pathology, IHC serves as a diagnostic, prognostic, and predictive method and IHC readings directly influence the management of patients in the clinical setting.
For example, the assessment of estrogen receptor α (ER-α), and human epidermal growth factor receptor 2 (HER2) by IHC in breast cancer patients is the definitive test to determine whether or not a patient will receive therapies that can cost as much as 0,000 per year.
Introduction Antibodies are among the most commonly used research tools, routinely used for Western blot (WB), immunoprecipitation (IP), enzyme-linked immunosorbent assays (ELISA), quantitative immunofluorescence (QIF), and immunohistochemistry (IHC).
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